Amazon Athena now provides an interface VPC endpoint

You can create an interface VPC endpoint to connect to Athena using the AWS console or AWS Command Line Interface (AWS CLI) commands. For more information, please see Creating an Interface Endpoint. When you use an interface VPC endpoint, communication between your VPC and Athena APIs is secure and stays within the AWS network.

This feature is available in all regions where Amazon Athena is available except EU (Stockholm) and US (GovCloud). There are no additional Athena costs to use this feature. Interface VPC endpoint charges apply.